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Des Formes Posologiques Pour Faciliter l’Utilisation des Médicaments
La prise de médicaments sous formes posologiques orales est considérée comme la méthode d’administration la plus simple, mais n’est pas sans présenter quelques difficultés. Les comprimés solides peuvent être gros, difficiles voire douloureux à avaler.Les formes posologiques telles que les granules et comprimés effervescents, les …
User-Friendly Dosage Forms, a Win-Win Situation for Patients and Pharma
The easiest and simplest route of drug administration is oral ingestion. Traditionally, this has been achieved using solid tablets or capsules, which are swallowed whole and break down in the gastrointestinal tract to release their active pharmaceutical ingredients.However, swallowing tablets is not always easy. Tablet …
Understanding What Patients Want In A Medicine
By Dr Thomas Hein, who is Senior Vice President Commercial and Regulatory Affairs at HERMES PHARMAEarlier this year, the US Food and Drug Administration (FDA) released a guidance for industry on the ‘Size, Shape, and Other Physical Attributes of Generic Tablets and Capsules’. In it, …
Why Size Matters When It Comes To Taking Medicine
By Dr Thomas Hein, who is Senior Vice President Commercial and Regulatory Affairs at HERMES PHARMASwallowing tablets or capsules is difficult for many, and size is just one of the problems Earlier this year, the US Food and Drug Administration (FDA) released a guidance for …
Tablet Innovation: Sizing Up the Value for Pharma
The FDA suggests that difficulty swallowing tablets and capsules can be addressed by controlling various physical attributes of the tablet or capsule. However, these recommendations fail to tackle the problem directly as patients still have to deal with dosage forms that are negatively impacting compliance …
Stretching Product Value through Reformulation Strategies
New formulations that enhance bioavailability, optimize drug-delivery profiles, reduce dosing frequency, or improve patient experience have the potential to deliver quicker returns on investments than developing a completely new drug…Written by Adeline Siew, the article has been published in Pharmaceutical Technology, Volume 38, Issue 10, pages …
The Advantages of Alternative Dosage Forms
While solid dosage forms such as tablets or capsules have been the go-to option for many years, recent data show that a substantial number of people have difficulty swallowing them. This can lead to poor compliance in many cases. How can Pharma combat this problem?When …
A User-centric Approach to Pharmaceuticals
Taking a ‘one-size-fits-all’ approach to pharmaceuticals is becoming less effective. With people demanding choice and convenience when it comes to their medication, the pharma industry must start putting patients’ needs at the heart of medicine manufacture and formulation development.In this article published in Doses, Dr …
A Hard Pill to Swallow: Improving Palatability
Difficulty swallowing tablets is a problem for all age groups, with some patients taking potentially dangerous steps to break up and swallow their medication. Such issues can influence patient compliance, so what can medicine manufacturers do to help overcome the problem?Dr. Thomas Hein (Senior Vice …
A Matter of Taste – Insights about the various approaches used in taste masking
The taste of orally administered medicines has important implications for patient compliance. However, most APIs have an unpleasant taste. Therefore, developing better tasting medicines is a major focus in pharmaceutical manufacturing – especially for user-friendly dosage forms, which spend longer in the mouth compared to …