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The TOPO Granulation Technology Used in the Manufacture of Effervescent Tablets
The effervescent tablet has proven to be a very user-friendly dosage form for the intake of pharmaceuticals. For the pharmaceutical industry, effervescent tablets represent a means to expand product lines, prolong product life cycles and thus expand market share.bene-Arzneimittel is a mid-sized, internationally-operating family business …
Problem-solving Ingredients for Complex Drugs
Around 40% of new chemical entities fall into class II – low solubility drugs, making them difficult to formulate. Improving the bioavailability of these compounds is a major challenge but the technologies involved could help to extend the lifecycle of many medicines. Manufacturers are also …
Hot Melt Coating Comes of Age
Effective medical treatment using self-administered medicines often hinges on patient compliance. This is particularly true when repeated or multiple doses are required, or for those patients who may find it difficult to swallow solid tablets, such as children, the elderly or people suffering from esophagitis. …
A Taste of Your Own Medicine
For example, solid tablets can be large, uncomfortable and even painful to swallow. Research has shown that factors including tablet size, shape and ease-of-swallowing can significantly affect treatment preference, adherence and, subsequently, effectiveness. Given these factors, there is an unmet market need for making medicines …
Putting The Fizz Into Formulation
Effervescent dosage forms offer a wide range of benefits. First and foremost, drinkable medicines are much easier to swallow than conventional solid tablets or capsules. This is worth noting, as many patients complain that swallowing tablets is painful and unpleasant, with factors such as tablet …
Can Pharma Defy Gravity at the Patent Cliff?
Generic-drug competition has become increasingly aggressive, especially in an environment where healthcare policies are placing stronger emphasis on pharmacoeconomics and demanding better treatment outcomes at a lower cost. A 2012 analysis by IMS Health estimated that patent expiries will reduce brand spending in developed markets …
Solvent-free Coating of Traditional and User-friendly Dosage Forms
Tablets and capsules are often coated for various reasons such as to improve their appearance or to make them easier to swallow. Coatings also play an important role in maintaining drug stability, activity, and effectiveness. This article reviews the benefits of solvent-free processes and techniques …
Power to the Patients
Modern patients enjoy access to a wealth of information via the internet, leading them to request specific treatments from their healthcare practitioners. Many patients also now pay for their own healthcare and are more involved in the treatment purchase decision. For these reasons, medicines that …
A Hard Pill to Swallow: Meeting the Needs of Modern Consumers
Confronted with the ‘patent cliff’, dwindling drug discovery success and a host of other challenges, pharmaceutical companies are being forced to reconsider how they can remain profitable. This includes a move towards actively placing the needs of the modern patient at the centre of their …
Putting Patients First
Pharma is looking to the over-the-counter market as an opportunity to reduce healthcare costs and promote self-administration. By creating medicines that patients choose to take, rather than have to take, forward-thinking companies can grow their market share, despite the challenging climate.This article has been written …