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From Bitter to Sweet: Developing a User-Friendly Painkiller
Caffeine is frequently added to common painkillers, such as acetaminophen, to increase their pain-relieving effect. Used primarily for mild to moderate pain, the acetaminophen plus caffeine combination is mostly produced in tablet form. Because of the extremely bitter taste of these APIs, formulation into other …
Swallowability by Design
Tablets are easy and cost-effective to manufacture, have good physical and chemical stability, and offer accurate dosing – it’s no surprise that they are the most common dosage form for prescription medicines. However, with patients of all ages having difficulties swallowing them, now is the …
User-Friendly OTC Dosage Forms Deliver Opportunity For Industry
Consumers expect choice and convenience in all aspects of their lives, including their medication. As such, the OTC industry must evolve to take advantage of this fact – manufacturers can breed brand loyalty and increase market share by offering consumers more convenience and a choice …
Germany Puts Focus on Pharma Innovation
The German pharmaceutical market is the largest in Europe and is predicted to grow to $65 billion by 2020. But where exactly is it headed in the future?This topic is explored in an article published in PharmaVOICE, where Dr Detlev Haack (Director of Research & …
Optimizing Dosage Forms for Improved Therapeutic Compliance
The oral route of administering medicines remains the most common for many reasons including cost, convenience and public familiarity. Of the oral dosage forms available, tablets and capsules are often the most well known and therefore the default choice for pharmaceutical and healthcare companies. However, …
Formulation Development & Manufacturing – Special Feature in DRUG DEVELOPMENT & DELIVERY
Contract development and manufacturing organizations (CDMOs) are constantly evolving, offering new services to customers to highlight their strengths and to differentiate themselves in the market place.In this Drug Development & Delivery Special Feature, Dr Martin Koeberle (Head of Analytical Development and Stability Testing at HERMES …
Innovation through User-Friendly Dosage Forms
Pharmaceutical companies are under constant pressure to innovate in order to increase revenue. Approaches that had been successfull in the past are increasingly falling short. Time for a closer look at user-friendly dosage forms as a concept to create additional value for patients.Interview conducted by …
The TOPO Granulation Technology Used in the Manufacture of Effervescent Tablets
The effervescent tablet has proven to be a very user-friendly dosage form for the intake of pharmaceuticals. For the pharmaceutical industry, effervescent tablets represent a means to expand product lines, prolong product life cycles and thus expand market share.bene-Arzneimittel is a mid-sized, internationally-operating family business …
Problem-solving Ingredients for Complex Drugs
Around 40% of new chemical entities fall into class II – low solubility drugs, making them difficult to formulate. Improving the bioavailability of these compounds is a major challenge but the technologies involved could help to extend the lifecycle of many medicines. Manufacturers are also …
Hot Melt Coating Comes of Age
Effective medical treatment using self-administered medicines often hinges on patient compliance. This is particularly true when repeated or multiple doses are required, or for those patients who may find it difficult to swallow solid tablets, such as children, the elderly or people suffering from esophagitis. …