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Some Like it Hot …
Pharmaceuticals are often administered via the oral route – a cheap, simple and safe approach. However, many active pharmaceutical ingredients (APIs) need to be effectively coated to ensure stability, efficacy and the desired API release profile. Hot melt coating (HMC) is becoming a go-to technique …
Hermes Highlights Need for Better Formats
In the pharmaceutical and food/dietary supplement industries, the oral route is considered a simple and cost-efficient way of delivery, with most products being traditionally formulated as solid tablets or capsules. However, consumer habits and demands are changing…To deliver medical and commercial success, pharmaceutical products will …
Des Formes Posologiques Pour Faciliter l’Utilisation des Médicaments
La prise de médicaments sous formes posologiques orales est considérée comme la méthode d’administration la plus simple, mais n’est pas sans présenter quelques difficultés. Les comprimés solides peuvent être gros, difficiles voire douloureux à avaler.Les formes posologiques telles que les granules et comprimés effervescents, les …
User-Friendly Dosage Forms, a Win-Win Situation for Patients and Pharma
The easiest and simplest route of drug administration is oral ingestion. Traditionally, this has been achieved using solid tablets or capsules, which are swallowed whole and break down in the gastrointestinal tract to release their active pharmaceutical ingredients.However, swallowing tablets is not always easy. Tablet …
Understanding What Patients Want In A Medicine
By Dr Thomas Hein, who is Senior Vice President Commercial and Regulatory Affairs at HERMES PHARMAEarlier this year, the US Food and Drug Administration (FDA) released a guidance for industry on the ‘Size, Shape, and Other Physical Attributes of Generic Tablets and Capsules’. In it, …
Why Size Matters When It Comes To Taking Medicine
By Dr Thomas Hein, who is Senior Vice President Commercial and Regulatory Affairs at HERMES PHARMASwallowing tablets or capsules is difficult for many, and size is just one of the problems Earlier this year, the US Food and Drug Administration (FDA) released a guidance for …
Tablet Innovation: Sizing Up the Value for Pharma
The FDA suggests that difficulty swallowing tablets and capsules can be addressed by controlling various physical attributes of the tablet or capsule. However, these recommendations fail to tackle the problem directly as patients still have to deal with dosage forms that are negatively impacting compliance …
Stretching Product Value through Reformulation Strategies
New formulations that enhance bioavailability, optimize drug-delivery profiles, reduce dosing frequency, or improve patient experience have the potential to deliver quicker returns on investments than developing a completely new drug…Written by Adeline Siew, the article has been published in Pharmaceutical Technology, Volume 38, Issue 10, pages …
The Advantages of Alternative Dosage Forms
While solid dosage forms such as tablets or capsules have been the go-to option for many years, recent data show that a substantial number of people have difficulty swallowing them. This can lead to poor compliance in many cases. How can Pharma combat this problem?When …