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Can Pharma Defy Gravity at the Patent Cliff?
Generic-drug competition has become increasingly aggressive, especially in an environment where healthcare policies are placing stronger emphasis on pharmacoeconomics and demanding better treatment outcomes at a lower cost. A 2012 analysis by IMS Health estimated that patent expiries will reduce brand spending in developed markets …
Solvent-free Coating of Traditional and User-friendly Dosage Forms
Tablets and capsules are often coated for various reasons such as to improve their appearance or to make them easier to swallow. Coatings also play an important role in maintaining drug stability, activity, and effectiveness. This article reviews the benefits of solvent-free processes and techniques …
Power to the Patients
Modern patients enjoy access to a wealth of information via the internet, leading them to request specific treatments from their healthcare practitioners. Many patients also now pay for their own healthcare and are more involved in the treatment purchase decision. For these reasons, medicines that …
A Hard Pill to Swallow: Meeting the Needs of Modern Consumers
Confronted with the ‘patent cliff’, dwindling drug discovery success and a host of other challenges, pharmaceutical companies are being forced to reconsider how they can remain profitable. This includes a move towards actively placing the needs of the modern patient at the centre of their …
Putting Patients First
Pharma is looking to the over-the-counter market as an opportunity to reduce healthcare costs and promote self-administration. By creating medicines that patients choose to take, rather than have to take, forward-thinking companies can grow their market share, despite the challenging climate.This article has been written …
Blend Uniformity – In the Mix
When manufacturing safe and effective drugs, it is essential that the amount of active pharmaceutical ingredient present in every dose is exactly the same. During production of solid oral dosage forms, the key challenge is to obtain a homogeneous blend before tableting or filling, in …
It’s no Choke!
Over 55% of people suffer from swallowing difficulties when taking tablets and/or capsules, according to a recent market study commissioned by HERMES PHARMA. It surveyed 2,000 people in the US and Germany and was conducted by market research expert Spiegel Institut Mannheim. The findings also …
Hot Melt Coating for Controlling the Stability, Release Properties and Taste of Solid Oral Dosage Forms
Traditional methods to coat solid oral dosage forms mostly use solvents, an approach that suffers from a range of drawbacks including cost, environmental concerns and lengthy processing times. Hot melt coating (HMC) is an innovative and effective alternative that is reliable, cheap and fast, while …