HERMES PHARMA’s new patent optimizes effervescent tablet manufacture, addressing consumer demand for ease of swallowing, choice and convenience.
The pharmaceutical industry faces a significant challenge: over 50% of people struggle to swallow conventional tablets and capsules. This difficulty, combined with shifting consumer and patient preferences towards more convenient and palatable options, is driving a resurgence in effervescent tablets. Recognizing this shift, HERMES PHARMA has developed and patented an innovative manufacturing method that further optimizes the production of effervescent tablets.
This advanced method addresses key challenges in the production process, such as improving granule stability, increasing dissolution efficiency, and reducing environmental impact.
Key benefits of the new effervescent tablet manufacturing method
The patented manufacturing method developed by HERMES PHARMA delivers a range of benefits:
- Enhanced effervescence
The patented method ensures a precisely managed effervescence reaction. Effervescent products using this method for pharmaceuticals or dietary supplements therefore benefit from a quick and efficient dissolution process, elevating the delivery and absorption of active ingredients. Meanwhile, the fast and complete effervescent means users experience a more pleasant and effective product. - High consistency and stability
By leveraging a controlled mixing process in a horizontally-aligned vacuum environment, the method offers consistency and granule stability. This results in consistent product performance across batches, ensuring reliable dosing and extended shelf life, even in challenging environmental conditions such as high humidity. - Added value for our customers
The method is designed for industrial-scale application, combining improved granulation technology with efficient drying processes to boost production speed while improving energy efficiency. The process ensures consistent production of high-quality effervescents while supporting our customers in meeting demand more effectively.
What is the new effervescent tablet manufacturing method all about?
Vacuum-assisted mixing chamber
The use of vacuum technology in the mixing chamber reduces air entrapment which promotes efficient heating and cooling cycles. Gentle product movement despite high stirring speed results in improved distribution of the granulation liquid, which ensures uniformity and thoroughly mixed components. This leads to consistent granule quality and high overall batch performance.
Tailored reaction control
The newly-patented method allows precise control over the acid-base reaction integral to effervescence, thus leading to high stability and quality of the end product.
Advanced drying process
The drying step in this method is optimized for preservation of the granules, long shelf-life and product reliability over time. This ensures long-lasting, high-quality products for both our customers as well as patients and consumers.
Flexibility in component range
The method’s adaptability accommodates a range of acids and bases, enabling customization for diverse product specifications and consumer needs. By adopting this method, pharmaceutical and nutraceutical companies can produce high-quality effervescent tablets that align with evolving consumer and patient preferences. What’s more, the method delivers significant benefits for healthcare companies, offering improved efficiency, quality, and scalability. Depending on ingredients, product and existing dossier, customers already using HERMES PHARMA’s established granulation technologies can seamlessly transition to this new method without requiring changes to their regulatory dossiers.
Patent protected
Products manufactured with this new process can be patent protected and marked accordingly. This offers our customers a key point of differentiation from the competition in saturated or crowded markets.
Want to read more about our effervescent evolution?
In the following article published by Tablets & Capsules (Volume 22 Issue 5) Wolfgang Schiemenz, Senior Manager Product Design & Process Development at HERMES PHARMA discusses:
- The limitations of traditional drug delivery methods and the rising demand for alternatives
- How well-formulated effervescent tablets address key consumer and patient needs as well as preferences
- The business value of expanding product lines to include effervescent formulation
- Our new patented manufacturing process that enhances efficiency while ensuring high quality – without introducing regulatory hurdle
- The future outlook for effervescent tablets in the pharmaceutical industry